In this study, it was aimed to examine whether psychological resilience is predicted by psychological well-being, self-efficacy, social support and demographic variables. Relational Survey Model, one of the quantitative research methods, was used in the research. The study group of the research consists of 224 university students residing in Istanbul in the 2022-2023 academic year. 164 (73.2%) of the participants were female and 60 (26.8%) were male. While collecting data, it was collected with easy sampling method and through Google form. As a measurement tool in the research; demographic information form, Psychological Well-Being Scale, General Self-Efficacy Scale, Multidimensional Scale of Perceived Social Support, Brief Psychological Resilience Scale were used. As a result of the regression analysis, it was seen that the variables explained 38% of psychological resilience. When the t-test results regarding the significance of the regression coefficients are examined, it is seen that psychological well-being, self-efficacy and gender are significant predictors of psychological resilience. Social support, age, number of siblings, mother's education level, father's education level, residence, parental attitude variables do not have a significant effect on psychological resilience.